Erectile Dysfunction in Patients With Coronary Artery Disease

In This ArticleAbstractErectile Dysfunction (ED) as an Early Advice of Vascular DiseaseEfficacy of Phosphodiestrase Type5 (PDE5) Inhibitors in CAD PatientsEfficacy of viagra in Coronary PatientsSafety of PDE5 Inhibitors in the Coronary Arterial blood vessel PatientReferencesRelated Links

Efficacy of sildenafil in Coronary Patients

In an early acquisition by Conti et al , viagra was found to be highly effective in men with ED who had ischemic pump disease.
In all, 70% of men reported improved erections with sildenafil.
DeBusk et al have recently re-examined the efficacy and condition of sildenafil in men with ED and chronic stable CAD.
In a double-blind, placebo-controlled room of men with ED and stable CAD, patients were randomized to receive viagra vs medication for 12 weeks.
Primary election outcomes were questions 3 and 4 of the IIEF.
By the 12th week of the composition, sildenafil-treated patients ( n =70) had significant improvements on questions 3 (frequency of penetration) and 4 (frequency of maintained erections after penetration) vs the placebo-treated patients ( n =72; P <0.01).
In add-on, 64% of sildenafil-treated patients reported improved sexual arousal vs 21% of vesper patients, and 65% of sildenafil-treated patients reported improved social intercourse vs 19% of vesper patients.
There were no serious drug-related cardiac events.
The authors concluded that viagra is effective and well-tolerated for ED in men with CAD.

Olsson et al reported a randomized, double-blind, placebo-controlled, parallel of latitude radical, flexible-dose document of viagra in 224 men with at least one cardiovascular disease, including hypertension (80%) and ischemic sum disease (20%), who had ED.
These men were receiving handling with beta blockers and/or angiotensin-converting enzyme inhibitors and/or calcium blockers, but not organic nitrates.
Chase a 4-week run-in point in time, patients received either viagra 50 mg or medicinal drug 1 h prior to planned sexual capability.
Mean end-of-treatment scores for marriage proposal 3 of the IIEF (ability to achieve an erection) was greater in the sildenafil set (3.7) than the medicine radical (2.2).
Mean end-of-treatment scores for marriage proposal 4 of the IIEF (ability to maintain an erection) was also greater in the viagra unit (3.3) than the medication set (1.9; P =0.0001).
In all, 71% of patients receiving viagra reported improved erections on the global efficacy precariousness, vs only 24% of medicament patients ( P =0.0001).
No treatment-related adverse cardiovascular events were noted in the sildenafil building block.

Thus, studies to date suggest that a high percent of men with CAD plus ED respond favorably to the PDE5 inhibitor viagra.
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